The Welsh Government is making £5.25m available to assist Welsh arts organisations, museums, libraries and independent cinemas through the winter.
Aimed at organisations at risk of closure or job losses due to Covid-19, the fund will cover activity from 1 October to 31 March. Applications will open on 12 January until 26 January.
The Welsh Government says the money is separate from a £120m package announced to assist businesses affected by the tightening of Covid restrictions.
Welsh Deputy Minister for Arts and Sport Dawn Bowden has asked organisations to think carefully if they need to make an application.
"It’s important funds are given to those in the most urgent need. This fund is about survival, it is not about compensating for temporarily reduced profits."