Guy's & St Thomas' Foundation says it will remove a statue of the London hospital's founder, Thomas Guy, to "a less prominent area" over his links to slavery.
It will need planning permission to do so - something its lawyers say is "very unlikely in the short to medium term due to planning legislation and political sentiment".
The plan for the listed statue conflicts with the Government's 'retain and explain' policy on contested heritage, and a final decision may lie in the hands of the Planning Minister, Robert Jenrick.
"Clearly, the minister is likely to give great weight to his policy which is not supportive of removing or otherwise altering the statue," the hospital's lawyers concluded, warning the removal plan may not succeed.
A consultation recommended the trust retain statues of Thomas Guy and historical benefactor Robert Clayton but provide information on how the men made their wealth. Clayton's statue will remain in place, as it's considered to be less prominent than Guy's.