Disabled artists will be able to apply for a share of £600,000 to bring their ideas to life.
A total of 14 awards will be made to disabled artists in England, Scotland and Wales to develop and present work across the country or internationally through Unlimited's UK and international open awards.
Cat Sheridan, Senior Producer at Unlimited, said the organisation is keen for applications for radical, ambitious and original ideas across a whole range of artforms, sizes and scales.
"We can't wait to discover what wonderful work this investment will support,” she said.
Pete Massey, Director North at Arts Council England, said: “Unlimited are changing the perception of disability and challenging the cultural sector by commissioning disabled artists, while also supporting people in all communities to express themselves creatively and experience arts and culture.
"I’m delighted that we are funding them as a National Portfolio Organisation and look forward to seeing the extraordinary work these awards will support.”
The deadline for applications is midday Monday 2 October.