A theatre sheltering over 1,000 people has been bombed in the southern Ukrainian city of Mariupol.
Satellite pictures show the word "children" had been marked in large letters outside the theatre.
The majority seeking refuge inside are thought to be children and elderly people.
In a video address, Ukraine's President Volodymyr Zelensky said Russia deliberately targeted the theatre: "Our hearts are broken by what Russia is doing to our people. To our Mariupol."
Earlier this week, a museum in the northern Ukrainian city of Chernihiv was severely damaged by Russian strikes.
The Tarnovski Chernihiv Regional Historical Museum, also home to a regional youth library, is one of Ukraine’s oldest historical museums.
The library was almost completing destroyed by bombing, according to museum director Serhiy Laevsky.
Writing on Facebook, he said the main museum is in “full order”. Its collection devoted to military history was moved to a secure location after its building was also damaged.
The museum survived shelling during the First and Second World Wars.